Anti-LMNA Monoclonal Antibody-抗体-抗体-生物在线
北京索莱宝科技有限公司
Anti-LMNA  Monoclonal Antibody

Anti-LMNA Monoclonal Antibody

商家询价

产品名称: Anti-LMNA Monoclonal Antibody

英文名称: Anti-Lamin A Monoclonal Antibody

产品编号: K000142M

产品价格: null

产品产地: 北京

品牌商标: Solarbio

更新时间: 2025-05-30T15:53:18

使用范围: WB

北京索莱宝科技有限公司
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Anti-LMNA Monoclonal Antibody

品牌:solarbio | 货号:K000142M

宿主Mouse
英文名称Anti-LMNA Monoclonal Antibody
别名CDCD1;CDDC;CMD1A;CMT2B1;EMD2;FPL;FPLD;FPLD2;HGPS;IDC;LDP1;LFP;LGMD1B;LMN1;LMNC;LMNL1;MADA;PRO1;Lamin A/C
应用WB
稀释比例WB 1:1000.
蛋白分子量74/65/71/64/63/69kDa
Gene ID4000
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG2a
免疫原Purified recombinant human LMNA protein fragments expressed in E.coli.
性状液体
Public Immunogen RangePurified recombinant human LMNA protein fragments expressed in E.coli.
Subcellular LocationsNucleus Nucleus envelope Nucleus lamina Nucleus speckle nucleoplasm
Swiss ProtP02545
克隆号3D6-F4-B7
克隆类型Monoclonal Antibody
背景资料The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.